Trichothecenes are exquisitely toxic to the gastrointestinal (GI) tract and leukocytes and thus are likely to impair gut immunity. International Nuclear Information System (INIS) T- 2 toxin impairment of enteric reovirus clearance in the mouse associated with suppressed immunoglobulin and IFN-γ responses These data indicate that acute exposure to moderate levels of T- 2 toxin may progressively impair the cation gradient across the jejunal epithelium. Increasing levels of T- 2 toxin negatively affected the ouabain-sensitive I(sc) in a cubic (P = 0.007) fashion. Compared to the vehicle control, the ouabain-sensitive I(sc) was negatively affected (P = 0.008) only under 5 μg of T- 2 toxin/ml. T- 2 toxin also did not statistically affect glucose-induced electrophysiological variables during the first 3 min of glucose induction. T- 2 toxin did not affect basal values of short circuit current (I(sc)), transmural potential difference, or tissue conductivity in the jejunal epithelium. Jejunal segments of broilers were monitored in Ussing chambers in the presence of T- 2 toxin at the levels of 0 (negative control), 0 (methanol/vehicle control), 0.1, 1, 5, and 10 μg/ml of buffer. The present investigations were conducted to test the effects of T- 2 toxin on electrophysiological variables of jejunal epithelium of chicken. Yunus, Agha Waqar Kröger, Susan Tichy, Alexander Zentek, Jürgen Böhm, Josef He has also published widely with 73 publications in International Journals and has several conference papers, book chapters and reports.Electrophysiological response of chicken's jejunal epithelium to increasing levels of T- 2 toxin. He has served as consultant for some leading Biotech companies in India. His current research interests include-Developing enzymes for biomass conversion, Glucose tolerant β-glucosidases, heterologous protein expression in fungi, and fungal genomics. He played the leading role in setting up the CBF’s lignocellulosic ethanol pilot plant, and the solid state enzyme production pilot plant at CSIR-NIIST. He has 20 years of research experience spanning diverse fields including fermentation technology, embryonic stem cell biology and transcriptomics, though currently he is working mainly on biomass conversion technologies. He is also the activity lead for the Centre for Biofuels (CBF) at CSIR-NIIST. Rajeev Sukumaran is heading the Biofuels and Biorefineries Section at the CSIR-National Institute for Interdisciplinary Science and Technology’s Microbial Processes and Technology Division., in Trivandrum, India.
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His primary research interest is to develop the sustainable process for bioconversion of lignocellulosics into renewable energy and biochemicals.Proactive research lead with entrepreneur mindset, that brings hands on strategic experience in research projects and startup of piloting to full commercial scale operations.ĭr. He has also co-edited 4 books on D-xylitol, lignocellulose degradation, extremophiles and Brazilian bioenergy development.
Overall, he has 16 years’ research experience working in industries and universities on biomass conversion into ethanol, industrial enzymes production and membrane based separations. He has published 52 articles in peer-reviewed journals and 16 book chapters. He is responsible for scientific leadership for deployment of cellulosic ethanol process at demonstration plant and scale up activities. Chandel is working as a lead scientist for cellulosic ethanol production at Centro de Tecnologia Canavieira (Sugarcane Technology Centre, CTC), Piracicaba, Brazil. To the technical, policy analysis, climate change, geo-political analysis of bioenergy and green transportation fuels at industrial scale.ĭr.To its coverage of technological updates on biomass collection, storage and use, biomass processing, microbial fermentation, catalysis, regeneration, solar energy and monitoring of renewable energy and recovery process.As a first uniquely focused scientific and technical literature on bioenergy production in the context of India.The following features of this book attribute its distinctiveness:
Hence, it is a useful resource to policy makers, policy analysts, techno-economic analysts and business managers who deal with commercialization and implementation of bio-based energy and other value-added products. This book presents important aspects on the large scale production of biofuels following a bio-refinery concept and its commercialization and sustainability issues. This book will provide assistance to the broad range of readers involved in the crude oil import and production renewable energy production biomass analysis and bioconversion greenhouse gas emissions techno-economic analysis and government policies for implementing biofuels in India.
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